One of the unique aspects of meiosis is the pairing and exchange of information between homologous chromosomes. Recombination is one of the main methods for recognition and pairing of homologous ...

Poly(ADP-ribose) polymerase inhibitors (PARPi) have shown promising clinical results in the treatment of ovarian cancer. Analysis of biomarker subgroups consistently revealed higher benefits for ...

Changes of plasma GARP-LTGFβ1 complex during chemoradiotherapy may predict survival in non-small cell lung cancer (NSCLC). Development and validation of a CT-based radiomic model combined with ...

Precision gene editing is crucial for treating genetic diseases, as it enables targeted correction of specific mutations. A Korean research team has become the first in the world to significantly ...

A research collaboration based in Kumamoto University (Japan) has clarified how homologous chromosome pairing--a process necessary for sperm and egg formation where paternally- and maternally-derived ...

Many different vaccinations have been developed and approved worldwide against severe acute respiratory syndrome 2 (SARS-CoV-2) in a remarkably short period. Although mass vaccinations have resulted ...

When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key repair process called homologous recombination, the cell uses loops in its ...

Sensitivity to ionizing radiation is compelling evidence that BRCA1-and BRCA2-deficient cells are defective in repair of DSBs. As discussed above, 2 separate pathways play major roles in DSB repair in ...

To the Editor: In their interesting paper, "Homologous-Blood Syndrome during Extracorporeal Circulation in Man," which was published in the June 20 issue of the Journal, Litwak et al. showed that the ...