Heart valve defects are a common cause of death in newborns. Scientists have discovered "Creld1" is a key gene for the development of heart valves in mice. The researchers were able to show that a ...

A global research collaborative including Medical University of South Carolina investigators report in today's Science Translational Medicine that defects in the primary cilia of the developing fetus ...

WASHINGTON (Reuters) - A non-surgically implanted heart valve meant to delay open heart surgery in children with congenital heart defects worked well for all but a few patients during a year of follow ...

A pioneering heart valve replacement that grows at the same rate as the organ does could transform lives of children with defects, scientists say. The prosthetic could remove the need for patients to ...

Mutations in a gene regulating the production of cilia are associated with the development of Bicuspid aortic valve (BAV), the most common heart valve birth defect. Mutations in ciliary genes cause ...

The heart pumps blood throughout the body to provide the needed oxygen and nutrients. In the heart, blood flows to get oxygen from the lungs to deliver to the cells. Some of the most important ...