NFL.com's Jeremy Bergman breaks down three must-know storylines in Thursday night's game between the San Francisco 49ers and ...

The next time 49ers running back Christian McCaffrey catches a touchdown pass, he'll have a unique achievement in NFL history ...

The 49ers may need Osa Odighizuwa more than ever after Alfred Collins' injury. Here's why the interior disruptor could be ...

With the 2026 NFL season upon us, Nick Shook ranks each team's quarterback, from 1 to 32, heading into Week 1. Who ranks ...

Nick Bosa says he's "100% ready to go" vs. the Rams and reveals the message he shared with Alfred Collins after his ...

Devastating news for the 49ers. Defensive tackle Alfred Collins suffered a season-ending patellar tendon injury, leaving the ...

George Kittle says he feels good ahead of Week 1 against the Rams and jokes about Kyle Shanahan's "step back" comment.

Get the latest Week 1 injury report, with Nick Bosa, George Kittle and nine others limited while James Thompson was the lone ...

When 49ers coach Kyle Shanahan met with the media early in the week, he had no doubt his team was going to face two of the ...

Kyle Shanahan says George Kittle and Nick Bosa will have their workloads managed vs. the Rams, while Christian McCaffrey is ...

Kyle Shanahan reacts to Aaron Donald skipping the Rams' trip to Australia, giving San Francisco a break ahead of its Week 1 ...

Week 1 power rankings vary widely across the NFL, offering a mixed picture of how national media views San Francisco ahead of ...