NFL.com's Jeremy Bergman breaks down three must-know storylines in Thursday night's game between the San Francisco 49ers and ...

The next time 49ers running back Christian McCaffrey catches a touchdown pass, he'll have a unique achievement in NFL history ...

The 49ers may need Osa Odighizuwa more than ever after Alfred Collins' injury. Here's why the interior disruptor could be ...

When 49ers coach Kyle Shanahan met with the media early in the week, he had no doubt his team was going to face two of the ...

With the 2026 NFL season upon us, Nick Shook ranks each team's quarterback, from 1 to 32, heading into Week 1. Who ranks ...

San Francisco 49ers head coach Kyle Shanahan laid out the team's plan for having Nick Bosa and George Kittle vs. the Los ...

George Kittle says he feels good ahead of Week 1 against the Rams and jokes about Kyle Shanahan's "step back" comment.

Kyle Shanahan discusses George Kittle, Nick Bosa, Christian McCaffrey, Aaron Donald and more ahead of Week 1 vs. the Rams in ...

There's a significant change to the San Francisco 49ers' depth chart following a brutal injury to one of their projected Week ...

NBC Sports Bay Area and NBC Bay Area will provide complete coverage of the 49ers’ season opener against the Rams in ...

Kyle Shanahan says George Kittle and Nick Bosa will have their workloads managed vs. the Rams, while Christian McCaffrey is ...

NBC Sports Bay Area and NBC Bay Area will provide complete coverage of the 49ers’ season opener against the Rams in ...