Primordial cardiomyocytes play an essential role in myocardial morphogenesis and coronary vascularization, but not in adult zebrafish heart regeneration.

Neural activity during the performance of a stereotyped behavioral task is often described as low-dimensional, occupying only a limited region in the space of all firing-rate patterns. This region has ...

The approach is solid, but the choice of learning rules, circuit architecture, and sparsity assumptions is not always sufficiently justified, and the model would benefit from a clearer mechanistic ...

The study provides important insight into the development of CD8 T cell virtual memory cells by identifying a dose-sensitive role for Bcl11b. The authors define the developmental stages affected by ...

Vocalizations of nonhuman primates, especially when acoustic and phylogenetic proximity is the highest, enhance human brain activity in the anterior temporal lobe.

This study presents valuable findings implicating Xkr and its newly identified binding partners in regulating the exposure of apoptotic signal for phagocytosis, suggesting that Xkr might facilitate ...

This valuable study combines free-flight kinematics, aerodynamic modeling, optogenetics, and connectomics to ask how Drosophila stabilize roll perturbations duri ...

This manuscript examines how overexpression of sphingosine 1-phosphate receptor 1 in a mouse model affects neutrophil distribution, metabolism and function. Given the significance of S1PR1 in ...

Researchers have created a detailed map of childhood Crohn’s disease before and after treatment which suggests anti-TNF therapy might push the pediatric cell ecosystem towards more resistant disease.

Learn more about eLife assessments Mosquito-borne virus transmission is increasing globally. Due to a lack of effective vaccines or targeted treatments, mitigation relies on reducing human exposure to ...

The oceans buffer against climate change via biogeochemical cycles underpinned by microbial metabolic activities. While planetary-scale surveys provide baseline microbiome data, inferring metabolic ...

The manuscript presents a compelling application of the microfluidic mother machine as a "selection" machine. While individual elements of the work have existed for many years across various research ...